Leading technologies for genetic disease modelling and substance exposure integrated with phenotypic evaluation in the zebrafish embryo.

Zebrafish animal model has been rapidly developing and is now recognized as a complementary system to rodents for studying bases of human diseases. The possibility of performing automated high-throughput screens at low-cost is unique for this model organism. DanioReadout offers a versatile pipeline with a palette of advanced tools for embryo manipulation and phenotype characterisation.

Genetic models development based on the CRISPR/Cas9 technology

  • Modeling a human genetic disorder
  • Gene and gene regulatory elements function investigation
  • Candidate genes verification

Zebrafish embryo compound exposure

  • Toxicological screens
  • Preclinical drug validation
  • Automated phenotype assessment

Cancer modelling service

  • Cancer growth and metastasis quantification
  • Cell culture based and patient-derived samples xenotransplantation
  • Service can be combined with potential therapeutics testing

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