Science

Our previous projects


Rothenbücher TSP, Ledin J, Gibbs D, ..., Persson C, Hulsart-Billström G, "Zebrafish embryo as a replacement model for initial biocompatibility studies of biomaterials and drug delivery systems.", Acta Biomater, 2019, 100, 235-243


Mustafa A, Roman E, Winberg S, "Boldness in Male and Female Zebrafish ( Danio rerio) Is Dependent on Strain and Test.", Front. Behav. Neurosci., 2019, 13, 248


Morikawa M, Mitani Y, Holmborn K, ..., Heldin CH, Miyazono K, "The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension.", Sci Signal, 2019, 12 (607), eaay4430


Debiais-Thibaud M, Simion P, Ventéo S, ..., Mazan S, Haitina T, "Skeletal Mineralization in Association with Type X Collagen Expression Is an Ancestral Feature for Jawed Vertebrates.", Mol. Biol. Evol., 2019, 36 (10), 2265-2276


Gudmundsson S, Wilbe M, Filipek-Górniok B, ..., Annerén G, Bondeson M, "TAF1, associated with intellectual disability in humans, is essential for embryogenesis and regulates neurodevelopmental processes in zebrafish.", Sci Rep, 2019, 9 (1), 10730


Silva WTAF, Sáez-Espinosa P, Torijo-Boix S, ..., Gómez-Torres MJ, Immler S, "The effects of male social environment on sperm phenotype and genome integrity.", J. Evol. Biol., 2019, 32 (6), 535-544


Alavioon G, Cabrera Garcia A, LeChatelier M, Maklakov AA, Immler S, "Selection for longer lived sperm within ejaculate reduces reproductive ageing in offspring.", Evolution Letters, 2019, 3 (2), 198-206


Ando K, Wang W, Peng D, ..., Mochizuki N, Betsholtz C, "Peri-arterial specification of vascular mural cells from naïve mesenchyme requires Notch signaling.", Development, 2019, 146 (2), dev165589


Alavioon G, Hotzy C, Nakhro K, ..., Maklakov AA, Immler S, "Haploid selection within a single ejaculate increases offspring fitness", Proc Natl Acad Sci USA, 2017, 114 (30), 8053-8058


Zajitschek S, Herbert-Read JE, Abbasi NM, Zajitschek F, Immler S, "Paternal personality and social status influence offspring activity in zebrafish.", BMC Evol. Biol., 2017, 17 (1), 157


Pujari-Palmer S, Lu X, Karlsson Ott M, "The Influence of Hydroxyapatite Nanoparticle Morphology on Embryonic Development in a Zebrafish Exposure Model.", Nanomaterials (Basel), 2017, 7 (4)


Vossen LE, Jutfelt F, Cocco A, Thörnqvist P, Winberg S, "Zebrafish (Danio rerio) behaviour is largely unaffected by elevated pCO2.", Conserv Physiol, 2016, 4 (1), cow065


Varshney GK, Carrington B, Pei W, ..., Sood R, Burgess SM, "A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish.", Nat Protoc, 2016, 11 (12), 2357-2375


Svensson J, Mustafa A, Fick J, Schmitz M, Brunström B, "Developmental exposure to progestins causes male bias and precocious puberty in zebrafish (Danio rerio).", Aquat. Toxicol., 2016, 177, 316-323


Lagman D, Franzén IE, Eggert J, Larhammar D, Abalo XM, "Evolution and expression of the phosphodiesterase 6 genes unveils vertebrate novelty to control photosensitivity.", BMC Evol. Biol., 2016, 16 (1), 124


Griffiths G, Müller F, Ledin J, ..., Press CM, Aleström P, "Fish from Head to Tail: The 9th European Zebrafish Meeting in Oslo.", Zebrafish, 2016, 13 (2), 132-137


Morikawa M, Koinuma D, Mizutani A, ..., Heldin CH, Miyazono K, "BMP Sustains Embryonic Stem Cell Self-Renewal through Distinct Functions of Different Krüppel-like Factors.", Stem Cell Reports, 2016, 6 (1), 64-73


Radomska KJ, Sager J, Farnsworth B, ..., Jazin E, Emilsson LS, "Characterization and Expression of the Zebrafish qki Paralogs.", PLoS ONE, 2016, 11 (1), e0146155


Varshney GK, Zhang S, Pei W, ..., Sood R, Burgess SM, "CRISPRz: a database of zebrafish validated sgRNAs.", Nucleic Acids Res., 2016, 44 (D1), D822-D826


Montazerolghaem M, Nyström L, Engqvist H, Karlsson Ott M, "Zebrafish: A possible tool to evaluate bioactive ions.", Acta Biomater, 2015, 19, 10-14


Wincent E, Stegeman JJ, Jönsson ME, "Combination effects of AHR agonists and Wnt/β-catenin modulators in zebrafish embryos: Implications for physiological and toxicological AHR functions.", Toxicol. Appl. Pharmacol., 2015, 284 (2), 163-179


Ebarasi L, Ashraf S, Bierzynska A, ..., Hildebrandt F, Majumdar A, "Defects of CRB2 cause steroid-resistant nephrotic syndrome.", Am. J. Hum. Genet., 2015, 96 (1), 153-161


Zajitschek S, Hotzy C, Zajitschek F, Immler S, "Short-term variation in sperm competition causes sperm-mediated epigenetic effects on early offspring performance in the zebrafish.", Proc. Biol. Sci., 2014, 281 (1785), 20140422


Hayes AJ, Reynolds S, Nowell MA, ..., Caterson B, Hammond CL, "Spinal deformity in aged zebrafish is accompanied by degenerative changes to their vertebrae that resemble osteoarthritis.", PLoS ONE, 2013, 8 (9), e75787


Filipek-Górniok B, Holmborn K, Haitina T, ..., Kreuger J, Ledin J, "Expression of chondroitin/dermatan sulfate glycosyltransferases during early zebrafish development.", Dev. Dyn., 2013, 242 (8), 964-975


Noonin C, Watthanasurorot A, Winberg S, Söderhäll I, "Circadian regulation of melanization and prokineticin homologues is conserved in the brain of freshwater crayfish and zebrafish.", Dev. Comp. Immunol., 2013, 40 (2), 218-226


Holmborn K, Habicher J, Kasza Z, ..., Kreuger J, Ledin J, "On the roles and regulation of chondroitin sulfate and heparan sulfate in zebrafish pharyngeal cartilage morphogenesis.", J. Biol. Chem., 2012, 287 (40), 33905-33916